Research Article|Articles in Press

White Spot Lesions: Biomaterials, Workflows and Protocols

Published:January 18, 2023DOI:


      The development of White Spot Lesions (WSLs) after completion of treatment is immensely discouraging to a specialty whose ultimate goal is to improve dentofacial aesthetics. This paper highlights state-of-the-art biomaterials that are used in the prevention, progression and treatment of WSLs, in the form of workflows to guide a clinician in decision-making at different treatment timings; before, during and after treatment. Scholarly literature has been screened until November 2022 for studies that assessed WSLs management. The mechanism of action and recommended mode of application have been elaborated upon. Additionally, the level of evidence of each treatment modality at different treatment timings has been highlighted according to its hierarchy. Although various attempts have been made to prevent, minimize, or treat WSLs, no clear guidelines for the management of WSLs are deemed to be a standardized protocol. By integrating currently available evidence based-clinical data, this review provides systematic flowcharts to guide clinicians in the decision-making process and patients about the prevention and treatment of the WSLs.
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