Abstract
The development of White Spot Lesions (WSLs) after completion of treatment is immensely
discouraging to a specialty whose ultimate goal is to improve dentofacial aesthetics.
This paper highlights state-of-the-art biomaterials that are used in the prevention,
progression and treatment of WSLs, in the form of workflows to guide a clinician in
decision-making at different treatment timings; before, during and after treatment.
Scholarly literature has been screened until November 2022 for studies that assessed
WSLs management. The mechanism of action and recommended mode of application have
been elaborated upon. Additionally, the level of evidence of each treatment modality
at different treatment timings has been highlighted according to its hierarchy. Although
various attempts have been made to prevent, minimize, or treat WSLs, no clear guidelines
for the management of WSLs are deemed to be a standardized protocol. By integrating
currently available evidence based-clinical data, this review provides systematic
flowcharts to guide clinicians in the decision-making process and patients about the
prevention and treatment of the WSLs.
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Published online: January 18, 2023
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