Seminars in Orthodontics
Volume 11, Issue 4 , Pages 209-218 , December 2005

Regulation of Growth in Mandibular Condylar Cartilage

  • Robert J. Hinton

      Affiliations

    • Department of Biomedical Sciences, Baylor College of Dentistry, Texas A&M University System Health Science Center, Dallas
    • Corresponding Author InformationAddress correspondence to Dr. Robert J. Hinton, Texas A&M University System Health Science Center, Baylor College of Dentistry, Department of Biomedical Sciences, 3302 Gaston Avenue, Dallas, TX 75246; Phone: (214) 828-8272; Fax: (214) 828-8951.
    • ,
  • David S. Carlson

      Affiliations

    • Department of Biomedical Sciences, Baylor College of Dentistry, Texas A&M University System Health Science Center, Dallas
    • Research and Graduate Studies, Texas A&M University System Health Science Center, College Station, TX

References 

  1. Weinmann JP , Sicher H . Bone and Bones. Fundamentals of Bone Biology . CV Mosby: St Louis; 1947;
  2. Scott JH . The growth of the human face . Proc R Soc Med . 1954;47:91–100
  3. Carlson DS . Biological rationale for early treatment of dentofacial deformities . Am J Orthod Dentofac Orthop . 2002;121:554–558
  4. Wright DM , Moffett B . The postnatal development of the human temporomandibular joint . Am J Anat . 1974;141:235–249
  5. Carlson DS , McNamara JA , Jaul DH . Histological analysis of the growth of the mandibular condyle in the rhesus monkey (Macaca mulatta) . Am J Anat . 1978;151:103–118
  6. Shibata S , Fukada K , Suzuki S , et al.   Immunohistochemistry of collagen types II and X, and enzyme-histochemistry of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible . J Anat . 1997;191:561–570
  7. Vinkka H . Secondary cartilages in the facial skeleton of the rat . Proc Finn Dent Soc . 1982;78:1–137
  8. Beresford WA . Chondroid Bone, Secondary Cartilage, and Metaplasia . Baltimore: Urban and Schwartzenberg; 1981;
  9. Hinton RJ . Response of the intermaxillary suture cartilage to alterations in masticatory function . Anat Rec . 1988;220:376–387
  10. Petrovic A . Mechanisms and regulation of mandibular condylar growth . Acta Morphol Neerl Scand . 1972;10:25–34
  11. Mizoguchi I , Nakamura M , Takahashi I , et al.   An immunohistochemical study of localization of type I and type II collagens in mandibular condylar cartilage compared with tibial growth plate . Histochemistry . 1990;93:593–599
  12. Silbermann M , Reddi AH , Hand AR , et al.   Further characterization of the extracellular matrix in the mandibular condyle in neonatal mice . J Anat . 1987;151:169–188
  13. Petrovic AG , Stutzmann JJ , Oudet CL . Control processes in the postnatal growth of the condylar cartilage of the mandible . In:  McNamara JA editors. Determinants of Mandibular Form and Growth . Ann Arbor, MI: Center for Human Growth and Development, University of Michigan; 1975;p. 101–154
  14. Carlson DS , McNamara JA , Graber LW , et al.   Experimental studies of growth and adaptation of TMJ . In:  Irby WB editors. Current Advances in Oral Surgery . Mosby: St Louis; 1980;p. 28–77
  15. Luder HU , Leblond CP , von der Mark K . Cellular stages in cartilage formation as revealed by morphometry, radioautography and type II collagen immunostaining of the mandibular condyle from weanling rats . Am J Anat . 1988;182:197–214
  16. Carlson DS . Growth of the temporomandibular joint . In:  Zarb GA ,  Carlsson GE ,  Sessle BJ , et al. editor. Temporomandibular Joint and Masticatory Muscle Disorders . Copenhagen: Munksgaard; 1994;p. 128–155
  17. Crompton AW . Development and adaptation of the temporomandibular joint . In:  Carlson DS ,  McNamara JA ,  Ribbens KA editor. Developmental Aspects of Temporomandibular Joint Disorders . Ann Arbor, MI: Center for Human Growth and Development, University of Michigan; 1985;p. 1–18
  18. Hall BK . The fate of adventitious and embryonic articular cartilage in the skull of the common fowl, Gallus Domesticus (Aves: Phasianidae) . Aust J Zool . 1968;16:795–805
  19. Hall BK . Immobilization and cartilage transformation into bone in the embryonic chick . Anat Rec . 1972;173:391–404
  20. Glineberg RW , Laskin DM , Blaustein DI . The effects of immobilization on the primate temporomandibular joint. A histologic and histochemical study . J Oral Maxillofac Surg . 1982;40:3–8
  21. Lydiatt DD , Davis LF . The effects of immobilization on the rabbit temporomandibular joint . J Oral Maxillofac Surg . 1985;43:188–193
  22. Duterloo HS , Wolters JM . Experiments on the significance of articular function as a stimulating chondrogenic factor for the growth of secondary cartilages of the rat mandible . Trans Eur Orthod Soc . 1971;103–115
  23. Engelsma SO , Jansen HWB , Duterloo HS . An in vivo transplantation study of growth of the mandibular condyle in a functional position in the rat . Archs Oral Biol . 1980;25:305–311
  24. Copray JCVM , Dibbets JMH , Kantomaa T . The role of condylar cartilage in the development of the temporomandibular joint . Angle Orthod . 1988;58:369–380
  25. Durkin J , Heeley J , Irving JT . The cartilage of the mandibular condyle . Oral Sci Rev . 1973;2:29–99
  26. Petrovic AG , Stutzmann JJ , Oudet CL . Defects in mandibular growth resulting from condylectomy and resection of the pterygoid and masseter muscles . In:  McNamara JA ,  Carlson DS ,  Ribbens KA editor. The Effect of Surgical Intervention on Craniofacial Growth, Monograph Number 12, Craniofacial Growth Series . Ann Arbor, MI: Center for Human Growth and Development, University of Michigan; 1982;p. 251–272
  27. Silbermann M , Weiss A , Toister Z , et al.   Studies on hormonal regulation of the growth of the craniofacial skeleton: I. Effects of a glucocorticoid hormone on cartilage calcification . J Craniofac Genet Dev Biol . 1981;1:285–298
  28. Maor G , Hochberg Z , Silbermann M . Growth hormone stimulates the growth of mouse neonatal condylar cartilage in vitro . Acta Endocrinol . 1989;120:526–532
  29. Silbermann M , Shurtz-Swirski R , Lewinson D , et al.   In vitro response of neonatal condylar cartilage to simultaneous exposure to the parathyroid hormone fragments 1-34,28-48, and 53-84 hPTH . Calcif Tissue Int . 1991;48:260–266
  30. Tajima Y , Kawasaki M , Kurihara K , et al.   Immunohistochemical profile of basic fibroblast growth factor and heparan sulfate in adult rat mandibular condylar cartilage . Arch Oral Biol . 1998;43:873–877
  31. Ogawa T , Shimozuma K , Fukada K , et al.   Localization and inhibitory effect of basic fibroblast growth factor on chondrogenesis in cultured mouse mandibular condyle . J Bone Miner Metab . 2003;21:145–153
  32. Fuentes MA , Opperman LA , Bellinger LL , et al.   IGF-1 and FGF-2 regulate cell proliferation of rat mandibular condylar cartilage in explant culture . Arch Oral Biol . 2002;47:643–654
  33. Molteni A , Modrowski D , Hott M , et al.   Differential expression of fibroblast growth factor receptor-1, -2, and -3 and syndecan-1, -2, and -4 in neonatal rat mandibular condyle and calvaria during osteogenic differentiation in vitro . Bone . 1999;24:337–347
  34. Visnapuu V , Peltomaki T , Ronning O , et al.   Distribution of fibroblast growth factors (FGFR-1 and -3) and platelet-derived growth factor receptors (PDGFR) in the rat mandibular condyle during growth . Orthod Craniofac Res . 2002;5:147–153
  35. Maor G , Laron Z , Eshet R , et al.   The early postnatal development of the murine mandibular condyle is regulated by endogenous insulin-like growth factor- I . J Endocrinol . 1993;137:21–26
  36. Xiao-Bing LI , Zhou Z , Luo S-J . Expressions of IGF-1 and TGF-α1 in the condylar cartilages of rapidly growing rats . Chin J Dent Res . 1998;2:52–56
  37. Visnapuu V , Peltomaki T , Ronning O , et al.   Growth hormone and insulin-like growth factor-I receptors in the temporomandibular joint of the rat . J Dent Res . 2001;80:1903–1907
  38. Maor G , Hochberg Z , Silbermann M . Insulin-like growth factor I accelerates proliferation and differentiation of cartilage progenitor cells in cultures of neonatal mandibular condyles . Acta Endocrinol . 1993;128:56–64
  39. Livne E , Laufer D , Blumenfeld I . Differential response of articular cartilage from young growing and mature old mice to IL-1 and TGF-beta . Arch Gerontol Geriatr . 1997;24:211–221
  40. Oberbauer AM , Peng R . Fractionation of growth plate chondrocytes (Differential expression of IGF-I and growth hormone and IGF-I receptor mRNA in purified populations) . Connect Tissue Res . 1995;31:179–187
  41. Deng C , Wynshaw-Boris A , Zhou F , et al.   Fibroblast growth factor receptor 3 is a negative regulator of bone growth . Cell . 1996;84:911–921
  42. Molteni A , Modrowski D , Hott M , et al.   Alterations of matrix- and cell-associated proteoglycans inhibit osteogenesis and growth response to fibroblast growth factor-2 in cultured rat mandibular condyle and calvaria . Cell Tissue Res . 1999;295:523–536
  43. Watahiki J , Yamaguchi T , Irie T , et al.   Gene expression profiling of mouse condylar cartilage during mastication by means of laser microdissection and cDNA array . J Dent Res . 2004;83:245–249
  44. Kronmiller JE , Upholt WB , Kollar EJ . Expression of epidermal growth factor mRNA in the developing mouse mandibular process . Arch Oral Biol . 1991;36:405–410
  45. Silbermann M , Weiss A , Raz E . Retardative effects of a corticosteroid hormone upon chondrocyte growth in the mandibular condyle of neonatal mice . J Craniofac Genet Dev Biol . 1981;1:109–122
  46. Lewinson D , Bialik GM , Hochberg Z . Differential effects of hypothyroidism on the cartilage and the osteogenic process in the mandibular condyle (recovery by growth hormone and thyroxine) . Endocrinology . 1994;135:1504–1510
  47. Ramirez-Yanez GO , Young WG , Daley TJ , et al.   Influence of growth hormone on the mandibular condylar cartilage of rats . Archs Oral Biol . 2004;49:585–590
  48. Collins DA , Becks H , Simpson ME , et al.   Growth and transformation of the mandibular joint in the rat: I. Normal female rats . J Orthod Oral Surg . 1946;32:431–442
  49. Hoskins WE , Asling CW . Influence of growth hormone and thyroxine on endochondral osteogenesis in the mandibular condyle and proximal tibial epiphysis . J Dent Res . 1977;56:509–517
  50. Livne E , Laufer D , Blumenfeld I . Comparison of in vitro response to growth hormone by chondrocytes from mandibular condyle cartilage of young and old mice . Calcif Tissue Int . 1997;61:62–67
  51. Copray JCVM , Brower N , Prins APA . Effects of polypeptide growth factors on mandibular condylar cartialge of the rat in vitro . J Biol Buccale . 1988;16:109–117
  52. Iseki S , Wilkie AOM , MorrissKay GM . Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault . Development . 1999;126:5611–5620
  53. Rice DPC , Aberg T , Chan Y-S , et al.   Integration of FGF and Twist in calvarial bone and suture development . Development . 2000;127:1845–1865
  54. Kronenberg HM . Developmental regulation of the growth plate . Nature . 2003;423:332–336
  55. Karaplis AC . PTHrP (novel roles in skeletal biology) . Curr Pharm Des . 2001;7:655–670
  56. Lanske B , Karaplis AC , Lee K , et al.   PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth . Science . 1996;273:663–666
  57. Vortkamp A , Lee K , Lanske B , et al.   Regulation of rate of cartilage differentiation by Indian Hedgehog and PTH-related protein . Science . 1996;273:613–622
  58. Alvarez J , Horton J , Sohn P , et al.   The perichondrium plays an important role in mediating the effects of TGF-beta on endochondral bone formation . Dev Dyn . 2001;221:311–321
  59. Long F , Linsenmayer TF . Regulation of growth region cartilage proliferation and differentiation by perichondrium . Development . 1998;125:1067–1073
  60. DiNino DL , Long F , Linsenmayer TF . Regulation of endochondral cartilage growth in the developing avian limb (cooperative involvement of perichondrium and periosteum) . Dev Biol . 2001;240:433–442
  61. Stutzmann J , Petrovic A . Intrinsic regulation of the condylar cartilage growth rate . Eur J Orthod . 1979;1:41–54
  62. Buxton PG , Hall B , Archer CW , et al.   Secondary chondrocyte-derived Ihh stimulates proliferation of periosteal cells during chick development . Development . 2003;130:4729–4739
  63. Murray PDF . Adventitious secondary cartilage in the chick embryo and the development of certain bones and articulations in the chick skull . Aust J Zool . 1963;368:368–430
  64. Charlier J-P , Petrovic A , Herrmann J . Determinisme de la croissance mandibulaire (effets de l’hyperpropulsion et de l’hormone somatotrope sur la croissance condylienne de jeunes rats) . Orthod Fr . 1968;39:567–579
  65. McNamara JA , Carlson DS . Quantitative analysis of temporomandibular joint adaptations to protrusive function . Am J Orthod . 1979;76:593–611
  66. Fuentes MA , Opperman LA , Buschang P , et al.   Lateral functional shift of the mandible: part II. Effects on gene expression in condylar cartilage . Am J Orthod Dentofac Orthop . 2003;123:160–166
  67. Hajjar D , Santos MF , Kimura ET . Propulsive appliance stimulates the synthesis of insulin-like growth factors I and II in the mandibular condylar cartilage of young rats . Arch Oral Biol . 2003;48:635–642
  68. Rabie ABM , Hagg U . Factors regulating mandibular condylar growth . Am J Orthod Dentofac Orthop . 2002;122:401–409
  69. Rabie ABM , She TT , Hagg U . Functional appliance therapy accelerates and enhances condylar growth . Am J Orthod Dentofac Orthop . 2003;123:40–48
  70. Tang GH , Rabie ABM , Hagg U . Indian hedgehog (a mechanotransduction mediator in condylar cartilage) . J Dent Res . 2004;83:434–438
  71. Blackwood HJJ . Cellular remodeling in articular tissue . J Dent Res . 1966;45(Suppl 3):480–489
  72. Thilander B , Carlsson GE , Ingervall B . Postnatal development of the human temporomandibular joint. I. A histological study . Acta Odontol Scand . 1976;34:117–126
  73. Öberg T , Fajers CM , Lohmander F , et al.   Autoradiographic studies with 3H-thymidine on cell proliferation and differentiation in the mandibular joint of young guinea pigs . Odontol Rev . 1967;18:327–344

 Supported in part by a grant from the American Association of Orthodontists Foundation (to RJH).

PII: S1073-8746(05)00042-3

doi: 10.1053/j.sodo.2005.07.005

Seminars in Orthodontics
Volume 11, Issue 4 , Pages 209-218 , December 2005

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